Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Comparative genomic hybridization of human breast tumor samples

ABSTRACT: Application of array comparative genomic hybridization (CGH) to the analysis of breast tumors

ORGANISM(S): Homo sapiens

SUBMITTER: Taku Tokuyasu

PROVIDER: E-TABM-170 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Breast tumor copy number aberration phenotypes and genomic instability.

Fridlyand Jane J Snijders Antoine M AM Ylstra Bauke B Li Hua H Olshen Adam A Segraves Richard R Dairkee Shanaz S Tokuyasu Taku T Ljung Britt Marie BM Jain Ajay N AN McLennan Jane J Ziegler John J Chin Koei K Devries Sandy S Feiler Heidi H Gray Joe W JW Waldman Frederic F Pinkel Daniel D Albertson Donna G DG

BMC cancer 20060418

<h4>Background</h4>Genomic DNA copy number aberrations are frequent in solid tumors, although the underlying causes of chromosomal instability in tumors remain obscure. Genes likely to have genomic instability phenotypes when mutated (e.g. those involved in mitosis, replication, repair, and telomeres) are rarely mutated in chromosomally unstable sporadic tumors, even though such mutations are associated with some heritable cancer prone syndromes.<h4>Methods</h4>We applied array comparative genom ...[more]

PMID: 16620391

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Dataset Information

Comparative genomic hybridization of human breast tumor samples

Publications

Breast tumor copy number aberration phenotypes and genomic instability.

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