Comparative genomic hybridization of Clostridium sporogenes and Clostridium botulinum strains

ABSTRACT: Clostridium botulinum is a heterogeneous Gram-positive species that comprises four genetically and physiologically distinct groups of bacteria that share the ability to produce botulinum neurotoxin, the most poisonous toxin known to man, and the causative agent of botulism, a severe disease of humans and animals. We report here the complete genome sequence of a representative of Group I (proteolytic) C. botulinum (strain Hall A, ATCC 3502). The genome consists of a chromosome (3,886,916 bp) and a plasmid (16,344 bp) which carry 3,650 and 19 predicted genes, respectively. Consistent with the proteolytic phenotype of this strain, the genome harbours a large number of genes encoding secreted proteases and enzymes involved in uptake and metabolism of amino acids. The genome also reveals a hith

ORGANISM(S): Clostridium botulinum

SUBMITTER: Andy Carter 

PROVIDER: E-TABM-264 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress