Dataset Information
Chromatin immunoprecipitation of transcription factor Dpf3 in mouse myoblast cells (C2C12) to identify genome wide binding sites
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Silke Sperling
PROVIDER: E-TABM-362 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.
Genes & development 20080901 17
Chromatin remodeling and histone modifications facilitate access of transcription factors to DNA by promoting the unwinding and destabilization of histone-DNA interactions. We present DPF3, a new epigenetic key factor for heart and muscle development characterized by a double PHD finger. DPF3 is associated with the BAF chromatin remodeling complex and binds methylated and acetylated lysine residues of histone 3 and 4. Thus, DPF3 may represent the first plant homeodomains that bind acetylated lys ...[more]
