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Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of peripheral blood from patients with intracranial aneurysm or intracranial aneurysm and subarachnoid haemorrhage

ABSTRACT: As the EU IP @neurIST Project aims at integrating biomedical informatics technologies in the assessment of rupture risks and treatments of cerebral aneurysms in humans. Genetic involvement in the disease is known, mRNA biomarkers will be searched as possible risk factors in easy to assess PBMCs (peripheral blood cells). The aim of this pilot study is specifically to check the clinical samples going from the patientï¾s bed side to the genomic analysis platform. Briefly, we hybridized biotin labelled cRNA from 2 controls (C1, C2), 1 patient bearing an intracranial aneurysm (I) and 1 patients bearing an intracranial aneurysm and subarachnoid haemorrhage (S). For each sample, one technical replicate was performed. Thus a total of 8 arrays was used.

ORGANISM(S): Homo sapiens

DISEASE(S): intracranial aneurysm and subarachnoid haemorrhage

SUBMITTER: Saliha Yilmaz

PROVIDER: E-TABM-421 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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