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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Comparative genomic hybridization of human breast cancer cell lines

ABSTRACT: AM_BreastCancerCellLineExpressionaCGH

ORGANISM(S): Homo sapiens

DISEASE(S): cancer

SUBMITTER: Anita Grigoriadis

PROVIDER: E-TABM-593 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines.

Mackay Alan A Tamber Narinder N Fenwick Kerry K Iravani Marjan M Grigoriadis Anita A Dexter Tim T Lord Christopher J CJ Reis-Filho Jorge S JS Ashworth Alan A

Breast cancer research and treatment 20090124 3

Tumour cell lines derived from breast cancer patients constitute one of the cornerstones of breast cancer research. To characterise breast cancer cell lines at the genetic level, we have developed a full tiling path bacterial artificial chromosome (BAC) array collection for comparative genomic hybridisation (aCGH). This aCGH BAC collection covers 98% of the entire human genome at a resolution of 40-60 kbp. We have used this platform alongside an in-house produced 17 K cDNA microarray set to char ...[more]

PMID: 19169812

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