Transcription profiling of rat heart from Lewis strain immunized with a peptide of human alpha1A-adrenergic receptor

ABSTRACT: Gene expression profiles in hearts of Lewis rats immunized with a peptide of human alpha1A-adrenergic receptor. The pathophysiological relevance of chronic autoantibodies against alpha-1A-adrenergic receptor stimulation in rats was investigated. Lewis rats were immunized using synthesized peptides of second extracellular loop of the human alpha-1A-adrenergic receptor and raised for one year. The gene expression in hearts of three immunized and three control rats were analyzed using Affymetrix Rat Genome 230 2.0 Arrays.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Oliver Hummel 

PROVIDER: E-TABM-725 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress