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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Chromatin immunoprecipitation of S. pombe followng nitrogen startvation to identfy binding sites of histone H3 C-terminus, H3K9ac and H4K5ac

ABSTRACT: Nitrogen starvation in the fission yeast yeast Schizosaccharomyces pombe causes nucleosome depletion in both promoters and coding regions of activated genes

ORGANISM(S): Schizosaccharomyces pombe

SUBMITTER: Jakub Orzechowski Westholm

PROVIDER: E-TABM-785 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Nitrogen depletion in the fission yeast Schizosaccharomyces pombe causes nucleosome loss in both promoters and coding regions of activated genes.

Kristell Carolina C Orzechowski Westholm Jakub J Olsson Ida I Ronne Hans H Komorowski Jan J Bjerling Pernilla P

Genome research 20100119 3

Gene transcription is associated with local changes in chromatin, both in nucleosome positions and in chemical modifications of the histones. Chromatin dynamics has mostly been studied on a single-gene basis. Those genome-wide studies that have been made primarily investigated steady-state transcription. However, three studies of genome-wide changes in chromatin during the transcriptional response to heat shock in the budding yeast Saccharomyces cerevisiae revealed nucleosome eviction in promote ...[more]

PMID: 20086243

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