Transcription profiling of fission yeast wild type and Pab2 knockout strains to invstigate the role of Pab2 in synthesis of noncoding snoRNAs

ABSTRACT: Here we used DNA microarrays to identify hyperadenylated transcripts detected in pab2 cells. Using this genome-wide approach, we found that the absence of Pab2 leads to the accumulation of polyadenylated snoRNAs and we describe the molecular mechanism of their accumulation.

ORGANISM(S): Schizosaccharomyces pombe

SUBMITTER: sanjay khadayate 

PROVIDER: E-TABM-843 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress