Transcription profiling of mouse embryonic stem cells exposed to cisplatin at four time points and concentrations to investigate DNA damage signalling pathways

ABSTRACT: To gain insight in the kinetics and interplay of the predominant transcriptional responses of DNA damage signalling pathways in undifferentiated cells, mouse embryonic stem cells were exposed to cisplatin at four different time points (2, 4, 8 and 24 hr) and concentrations (1, 2, 5 and 10 uM). RNA was isolated and subjected to genome-wide expression profiling.

ORGANISM(S): Mus musculus

SUBMITTER: Jan Polman 

PROVIDER: E-TABM-89 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress