Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Bordetella parapertussis strains isolated from humans and sheep


ABSTRACT: Global gene expression profiles were measured for B. parapertussis strains isolated from humans and sheep

INSTRUMENT(S): Scanning hardware

ORGANISM(S): Bordetella pertussis

SUBMITTER: Craig Cummings 

PROVIDER: E-TABM-95 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Genomic features of Bordetella parapertussis clades with distinct host species specificity.

Brinig Mary M MM   Register Karen B KB   Ackermann Mark R MR   Relman David A DA  

Genome biology 20060101 9


<h4>Background</h4>The respiratory pathogen Bordetella parapertussis is a valuable model in which to study the complex phenotype of host specificity because of its unique two-species host range. One subset of strains, including the sequenced representative, causes whooping cough in humans, while other strains infect only sheep. The disease process in sheep is not well understood, nor are the genetic and transcriptional differences that might provide the basis for host specificity among ovine and  ...[more]

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