Unknown,Transcriptomics,Genomics

Dataset Information

0

Transcription profiling of mouse macropages infected with Bacillus anthrasis

ABSTRACT: B.anthracis is able to grow and infect through macrophages, and it is unclear how the bacterium is able to escape the normal killing function of the macrophage. We hope the identification of novel genes will help us to understand the pathogenesis.

ORGANISM(S): Mus musculus

SUBMITTER: Renee Rubio 

PROVIDER: E-TIGR-84 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

Murine macrophage transcriptional responses to Bacillus anthracis infection and intoxication.

Bergman Nicholas H NH   Passalacqua Karla D KD   Gaspard Renee R   Shetron-Rama Lynne M LM   Quackenbush John J   Hanna Philip C PC  

Infection and immunity 20050201 2

Interactions between Bacillus anthracis and host macrophages represent critical early events in anthrax pathogenesis, but their details are not clearly understood. Here we report the first genomewide characterization of the transcriptional changes within macrophages infected with B. anthracis and the identification of several hundred host genes that were differentially expressed during this intracellular stage of infection. These loci included both genes that are known to be regulated differenti  ...[more]

Similar Datasets

Transcriptomics Transcription profiling of heart tissue among both sexes and three different strains of mouse, part 2
2005-01-01 | E-TIGR-86 | biostudies-arrayexpress
Transcriptomics Transcription profiling of heart tissue among both sexes and three different strains of mouse, part 1
2005-01-01 | E-TIGR-85 | biostudies-arrayexpress
Transcriptomics Transcription profiling of asthma induced mice treated with LPS in a controlled environment
2005-01-01 | E-TIGR-8 | biostudies-arrayexpress
Transcriptomics Transcription profiling of mice fed salt water to induce hypertension to assess strain and sex specific differences
2005-01-27 | E-TIGR-107 | biostudies-arrayexpress
Transcriptomics Transcription profiling of lung from Dahl salt sensitive (SS) rats and SS11BN consomic rats during hypoxia treatment
2006-09-15 | E-TIGR-116 | biostudies-arrayexpress
Transcriptomics Transcription profiling of rat lung response to hypoxia of the Dahl salt sensative (SS) rat and SS13BN cosomic rat SS13BN rats are derived from introgression of chromosome 13 from the Brown Norway (BN) rat into the SS genetic background
2005-01-01 | E-TIGR-63 | biostudies-arrayexpress
Transcriptomics Transcription profiling of heart during hypoxia of the Fawn Hooded Hypertensive (FHH) rat and FHH12BN consomic rat
2006-09-15 | E-TIGR-111 | biostudies-arrayexpress
Transcriptomics Transcription profiling of rat kidney response to hypoxia of the Dahl salt sensitive (SS) rat and SS7BN consomic rat SS7BN rats are derived from introgression of chromosome 7 from the Brown Norway (BN) rat into the SS genetic background
2005-01-01 | E-TIGR-73 | biostudies-arrayexpress
Transcriptomics Transcription profiling of rat liver response to hypoxia treatment of parental salt sensitive (SS) and consomic Brown Norway (SS7BN) rat strain SS7BN rats are derived from introgression of chromosome 7 from BN rats into the SS genetic background
2005-01-01 | E-TIGR-74 | biostudies-arrayexpress
Transcriptomics Transcription profiling of heart hypoxia response of rat strains FHH (Fawn Hooded Hypertensive) and BN (Brown Norway)
2005-01-01 | E-TIGR-58 | biostudies-arrayexpress