Dataset Information
Transcription profiling of wild type vs wild type yeast with controls spiked in different ratios; 1:1, 1:2 and 1:10 respectively
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Dik van Leenen
PROVIDER: E-UMCU-1 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Monitoring global messenger RNA changes in externally controlled microarray experiments.
EMBO reports 20030401 4
Expression profiling is a universal tool, with a range of applications that benefit from the accurate determination of differential gene expression. To allow normalization using endogenous transcript levels, current microarray analyses assume that relatively few transcripts vary, or that any changes that occur are balanced. When normalization using endogenous genes is carried out, changes in expression levels are calculated relative to the behaviour of most of the transcripts. This does not refl ...[more]
