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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Stationary phase timecourse

ABSTRACT: Nine day glucose starvation stationary phase culture, exit and entry from quiescence

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Jean-Christophe Andrau

PROVIDER: E-UMCU-12 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Genome-wide analyses reveal RNA polymerase II located upstream of genes poised for rapid response upon S. cerevisiae stationary phase exit.

Radonjic Marijana M Andrau Jean-Christophe JC Lijnzaad Philip P Kemmeren Patrick P Kockelkorn Thessa T J P TT van Leenen Dik D van Berkum Nynke L NL Holstege Frank C P FC

Molecular cell 20050401 2

The resting state of eukaryotic cells (G0) is relatively uncharacterized. We have applied DNA microarray expression profiling of S. cerevisiae to reveal multiple transitions during a complete 9-day growth cycle between stationary phase (SP) exit and entry. The findings include distinct waves of transcription after the diauxic shift (DS), identification of genes active in SP, and upregulation of over 2500 genes during the first minutes of lag phase. This provides a framework for analyzing large-s ...[more]

PMID: 15837421

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