Sampling Considerations for Wastewater Surveillance of Antibiotic Resistance in Fecal Bacteria.

ABSTRACT: Wastewaters can be analyzed to generate population-level data for public health surveillance, such as antibiotic resistance monitoring. To provide representative data for the contributing population, bacterial isolates collected from wastewater should originate from different individuals and not be distorted by a selection pressure in the wastewater. Here we use Escherichia coli diversity as a proxy for representativeness when comparing grab and composite sampling at a major municipal wastewater treatment plant influent and an untreated hospital effluent in Gothenburg, Sweden. All municipal samples showed high E. coli diversity irrespective of the sampling method. In contrast, a marked increase in diversity was seen for composite compared to grab samples from the hospital eff

SUBMITTER: Huijbers PMC 

PROVIDER: S-EPMC10002399 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature