Effect of antiretroviral therapy care interruptions on mortality in children living with HIV.

ABSTRACT:

Objective

To evaluate the characteristics and outcomes of HIV-infected children that have care interruptions, during which the child's health status and use of medication is unknown.

Design

We included data on children initiating ART between 2004 and 2016 at less than 16 years old at 16 International Epidemiologic Databases to Evaluate AIDS Southern Africa cohorts. Children were classified as loss to follow up (LTFU) if they had not attended clinic for more than 180 days. Children had a care interruption if they were classified as LTFU, and subsequently returned to care. Children who died within 180 days of ART start were excluded.

Methods

The main outcome was all cause mortality. Two exposed groups were considered: those with a first care interruption within the firs

SUBMITTER: Davies C 

PROVIDER: S-EPMC10002475 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature