Modelling the Pan-European Economic Burden of Alzheimer's Disease.

ABSTRACT:

Background

Recent advances open the opportunity of altering the course of Alzheimer's disease (AD) through lifestyle-based modifications and novel therapies. Ensuring that society is investing limited budgets in the interventions that have the greatest potential to generate tangible impact will require tools to guide policymakers.

Objectives

To build on previous studies to develop an economic model that estimates the societal burden of AD and evaluates the potential impact of novel interventions in six large European countries.

Design

AD progression was modelled using a published Markov structure with a 40-year time horizon to estimate lifetime costs and life years in a cohort aged 65 years and above diagnosed with mild cognitive impairment due to AD (MCI-AD) in 2020.

SUBMITTER: Martins R 

PROVIDER: S-EPMC10002890 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature