Seminal Extracellular Vesicles and Their Involvement in Male (In)Fertility: A Systematic Review.

ABSTRACT: Seminal plasma contains numerous extracellular vesicles (sEVs). Since sEVs are apparently involved in male (in)fertility, this systematic review focused on studies specifically investigating such relationship. Embase, PubMed, and Scopus databases were searched up to 31 December 2022, primarily identifying a total of 1440 articles. After processing for screening and eligibility, 305 studies were selected as they focused on sEVs, and 42 of them were considered eligible because they included the word fertility or a related word such as infertility, subfertility, fertilization, and recurrent pregnancy loss in the title, objective(s), and/or keywords. Only nine of them met the inclusion criteria, namely (a) conducting experiments aimed at associating sEVs with fertility concerns and (b) isolati

SUBMITTER: Parra A 

PROVIDER: S-EPMC10002921 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature