Pan-Cancer Analysis Reveals Functional Similarity of Three lncRNAs across Multiple Tumors.

ABSTRACT: Long non-coding RNAs (lncRNAs) are emerging as key regulators in many biological processes. The dysregulation of lncRNA expression has been associated with many diseases, including cancer. Mounting evidence suggests lncRNAs to be involved in cancer initiation, progression, and metastasis. Thus, understanding the functional implications of lncRNAs in tumorigenesis can aid in developing novel biomarkers and therapeutic targets. Rich cancer datasets, documenting genomic and transcriptomic alterations together with advancement in bioinformatics tools, have presented an opportunity to perform pan-cancer analyses across different cancer types. This study is aimed at conducting a pan-cancer analysis of lncRNAs by performing differential expression and functional analyses between tumor and non-neo

SUBMITTER: Khazaal A 

PROVIDER: S-EPMC10003012 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature