Effects of Terahertz Radiation on the Aggregation of Alzheimer's Aβ42 Peptide.

ABSTRACT: The pathophysiology of Alzheimer's disease is thought to be directly linked to the abnormal aggregation of β-amyloid (Aβ) in the nervous system as a common neurodegenerative disease. Consequently, researchers in many areas are actively looking for factors that affect Aβ aggregation. Numerous investigations have demonstrated that, in addition to chemical induction of Aβ aggregation, electromagnetic radiation may also affect Aβ aggregation. Terahertz waves are an emerging form of non-ionizing radiation that has the potential to affect the secondary bonding networks of biological systems, which in turn could affect the course of biochemical reactions by altering the conformation of biological macromolecules. As the primary radiation target in this investigation, the in vitro modeled Aβ42 aggr

SUBMITTER: Wang L 

PROVIDER: S-EPMC10003266 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature