Key Stratification of Microbiota Taxa and Metabolites in the Host Metabolic Health-Disease Balance.

ABSTRACT: Human gut microbiota seems to drive the interaction with host metabolism through microbial metabolites, enzymes, and bioactive compounds. These components determine the host health-disease balance. Recent metabolomics and combined metabolome-microbiome studies have helped to elucidate how these substances could differentially affect the individual host pathophysiology according to several factors and cumulative exposures, such as obesogenic xenobiotics. The present work aims to investigate and interpret newly compiled data from metabolomics and microbiota composition studies, comparing controls with patients suffering from metabolic-related diseases (diabetes, obesity, metabolic syndrome, liver and cardiovascular diseases, etc.). The results showed, first, a differential composition of the

SUBMITTER: Torres-Sanchez A 

PROVIDER: S-EPMC10003303 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature