Vitiligo, from Pathogenesis to Therapeutic Advances: State of the Art.
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ABSTRACT:
SUBMITTER: Diotallevi F
PROVIDER: S-EPMC10003418 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
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Vitiligo, from Pathogenesis to Therapeutic Advances: State of the Art.
Diotallevi Federico F Gioacchini Helena H De Simoni Edoardo E Marani Andrea A Candelora Matteo M Paolinelli Matteo M Molinelli Elisa E Offidani Annamaria A Simonetti Oriana O
International journal of molecular sciences 20230303 5
Vitiligo is an acquired hypopigmentation of the skin due to a progressive selective loss of melanocytes; it has a prevalence of 1-2% and appears as rounded, well-demarcated white macules. The etiopathology of the disease has not been well defined, but multiple factors contribute to melanocyte loss: metabolic abnormalities, oxidative stress, inflammation, and autoimmunity. Therefore, a convergence theory was proposed that combines all existing theories into a comprehensive one in which several me ...[more]
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