Inapparent infections shape the transmission heterogeneity of dengue.

ABSTRACT: Transmission heterogeneity, whereby a disproportionate fraction of pathogen transmission events result from a small number of individuals or geographic locations, is an inherent property of many, if not most, infectious disease systems. For vector-borne diseases, transmission heterogeneity is inferred from the distribution of the number of vectors per host, which could lead to significant bias in situations where vector abundance and transmission risk at the household do not correlate, as is the case with dengue virus (DENV). We used data from a contact tracing study to quantify the distribution of DENV acute infections within human activity spaces (AS), the collection of residential locations an individual routinely visits, and quantified measures of virus transmission heterogeneity from

SUBMITTER: Vazquez-Prokopec GM 

PROVIDER: S-EPMC10003742 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature