Electro-Oxidative C3-Selenylation of Pyrido[1,2-a]pyrimidin-4-ones.

ABSTRACT: In this work, we achieved a C3-selenylation of pyrido[1,2-a]pyrimidin-4-ones using an electrochemically driven external oxidant-free strategy. Various structurally diverse seleno-substituted N-heterocycles were obtained in moderate to excellent yields. Through radical trapping experiments, GC-MS analysis and cyclic voltammetry study, a plausible mechanism for this selenylation was proposed.

SUBMITTER: Shi J 

PROVIDER: S-EPMC10005275 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature