Effects of Parental Dietary Restriction on Offspring Fitness in Drosophila melanogaster.

ABSTRACT: Dietary restriction (DR) is a well-established strategy to increase lifespan and stress resistance in many eukaryotic species. In addition, individuals fed a restricted diet typically reduce or completely shut down reproduction compared to individuals fed a full diet. Although the parental environment can lead to changes epigenetically in offspring gene expression, little is known about the role of the parental (F₀) diet on the fitness of their offspring (F₁). This study investigated the lifespan, stress resistance, development, body weight, fecundity, and feeding rate in offspring from parental flies exposed to a full or restricted diet. The offspring flies of the parental DR showed increases in body weight, resistance to various stressors, and lifespan, but the deve

SUBMITTER: Lee HY 

PROVIDER: S-EPMC10005678 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature