The future burden of oesophageal and stomach cancers attributable to modifiable behaviours in Australia: a pooled cohort study.

ABSTRACT:

Background

We quantified the individual and joint contribution of contemporaneous causal behavioural exposures on the future burden of oesophageal and stomach cancers and their subtypes and assessed whether these burdens differ between population groups in Australia, as such estimates are currently lacking.

Methods

We combined hazard ratios from seven pooled Australian cohorts (N = 367,058) linked to national cancer and death registries with exposure prevalence from the 2017-2018 National Health Survey to estimate Population Attributable Fractions (PAFs) with 95% confidence intervals (CIs), accounting for competing risk of death.

Results

Current and past smoking explain 35.2% (95% CI = 11.7-52.4%), current alcohol consumption exceeding three drinks/day 15.7% (95% CI =

SUBMITTER: Laaksonen MA 

PROVIDER: S-EPMC10006078 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature