Role of magnetic resonance imaging for preoperative prediction of early biochemical failure in localized prostate cancer.

ABSTRACT:

Background

The purpose of our study was to assess preoperative clinical biological and Magnetic Resonance Imaging (MRI) predictive factors of early biochemical failure (BF), defined as persistence of significant post-operative plasmatic prostate specific antigen (PSA) level after radical prostatectomy (RP) in patients with localized prostate cancer (PCa).

Methods

In a retrospective cohort study we included 142 patients from our university hospital with newly diagnosed PCa, who underwent 3T multiparametric MRI prior to RP. Only the MRI target lesions [Prostate Imaging Reporting and Data System (PIRADS) ≥3] with histological correspondence were considered significant. Clinical, biological, MRI and pathological preoperative data were studied. We performed univariate and multiva

SUBMITTER: Cassin J 

PROVIDER: S-EPMC10006114 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature