Combining microfluidic paper-based platform and metal-organic frameworks in a single device for phenolic content assessment in fruits.

ABSTRACT: A microfluidic paper-based device (µPAD) has been combined with metal-organic frameworks (MOFs) for total phenolic compounds (TPC) quantification in fruit samples for the first time. The performance of the µPAD, based upon the vertical flow approach, was enhanced in order to determine the TPC content with high accuracy in fruit samples. The method was based on the traditional Folin-Ciocalteu Index using gallic acid or oenotannin as reference phenolic compounds. This novel design and construction of the device are in agreement with the principles of Green Chemistry avoiding wax technology (lower toxicity). The analytical parameters that affect the colorimetric method (using digital imaging of the colored zone) performance were optimized including design, sample volume, and MOF amount. Then,

SUBMITTER: Martinez-Perez-Cejuela H 

PROVIDER: S-EPMC10006271 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature