Adverse impact of tumor deposits in lymph node negative rectal cancer - a national cohort study.

ABSTRACT:

Purpose

This study aimed to investigate the prognostic effect of tumor deposits (TDs) in lymph node negative rectal cancer.

Methods

Patients who had undergone surgery for rectal cancer with curative intention between 2011 and 2014 were extracted from the Swedish Colorectal Cancer Registry. Patients with positive lymph nodes, undisclosed TD status, stage IV disease, non-radical resections, or any outcome (local recurrence (LR), distant metastasis (DM) or mortality) within 90 days after surgery were excluded. TDs status was based on histopathological reports. Cox-regression analyses were used to examine the prognostic impact of TDs on LR, DM, and overall survival (OS) in lymph node-negative rectal cancer.

Results

A total of 5455 patients were assessed for inclusion of w

SUBMITTER: Lundstrom S 

PROVIDER: S-EPMC10006276 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature