Dataset Information

Highlights from the 24th workshop on vitamin D in Austin, September 2022.

ABSTRACT: The 24th Workshop on Vitamin D was held September 7-9, 2022 in Austin, Texas and covered a wide diversity of research in the vitamin D field from across the globe. Here, we summarize the meeting, individual sessions, awards and presentations given.

SUBMITTER: Meyer MB

PROVIDER: S-EPMC10006320 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Highlights from the 24th workshop on vitamin D in Austin, September 2022.

Meyer Mark B MB Bernal-Mizrachi Carlos C Bikle Daniel D DD Biyani Madhu M Campbell Moray J MJ Chaudhari Snehal N SN Christakos Sylvia S Ingles Sue A SA Knuth Megan M MM Lee Seong Min SM Lisse Thomas S TS Liu Eva S ES Piec Isabelle I Plum Lori A LA Rao Sudhaker D SD Reynolds Carmen J CJ Thacher Tom D TD White John H JH Cantorna Margherita T MT

The Journal of steroid biochemistry and molecular biology 20230110

The 24th Workshop on Vitamin D was held September 7-9, 2022 in Austin, Texas and covered a wide diversity of research in the vitamin D field from across the globe. Here, we summarize the meeting, individual sessions, awards and presentations given. ...[more]

PMID: 36639037

Similar Datasets

Project description:BackgroundEnterovirus D68 (EV-D68) is a re-emerging pathogen that is particularly common in children and may cause asthma-like respiratory infection and acute flaccid myelitis. However, in Korea, EV-D68 has never been reported thus far. This study aimed to identify EV-D68 from nasopharyngeal aspirates (NPAs) in Korean children with a respiratory tract infection.Materials and methodsThe EV-D68 reference strain was purchased and blindly used to assess the detection ability of three commercial and one in-house mRT-PCR kit in 2018. Then, we selected children whose specimens were positive for human rhinovirus (HRV) and/or enterovirus (EV) by Allplex mRT-PCR (Seegene, Inc., Seoul, Korea) from April to December 2022. Total RNA was extracted from NPAs, and a partial 5'-UTR gene was amplified and sequenced for the identification of HRV/EV species. Additionally, PCR targeting the VP1 gene was performed to assess EV-D68-positive NPAs, followed by sequencing. Phylogenetic analysis and comparison of amino acid sequence alignments were performed using a partial VP1 gene of our and recent international EV-D68 strains.ResultsAmong the mRT-PCR kits tested, only the in-house kit was able to detect EV-D68 in 2018. However, we detected three EV-D68 strains among children hospitalized with fever and/or respiratory symptoms in September - December 2022 who tested positive for EV by the Allplex kit. Two of them were healthy toddlers with lower respiratory infections accompanied by new-onset wheezing but no neurologic complications. Among 34 children with lower respiratory infection who tested positive for HRV during the same period, EV-D68 was not detected. Phylogenetic analysis revealed that the first Korean EV-D68 belonged to subclade B3. Amino acid sequence alignment of international subclade B3 EV-D68 strains also showed that our strain is genetically more related to those from Europe than those from Japan.ConclusionWe first detected EV-D68 in three Korean children who had EV detected by the Allplex mRT-PCR kit in 2022. EV-D68 also circulated in Korea in fall 2022, but the prevalence and severity seemed to be lower than those in previous reports from other countries.

Dataset Information

Highlights from the 24th workshop on vitamin D in Austin, September 2022.

Publications

Highlights from the 24th workshop on vitamin D in Austin, September 2022.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets