Ambient fine particulate exposure and subcortical gray matter microarchitecture in 9- and 10-year-old children across the United States.

ABSTRACT: Neuroimaging studies showing the adverse effects of air pollution on neurodevelopment have largely focused on smaller samples from limited geographical locations and have implemented univariant approaches to assess exposure and brain macrostructure. Herein, we implement restriction spectrum imaging and a multivariate approach to examine how one year of annual exposure to daily fine particulate matter (PM_2.5), daily nitrogen dioxide (NO₂), and 8-h maximum ozone (O₃) at ages 9-10 years relates to subcortical gray matter microarchitecture in a geographically diverse subsample of children from the Adolescent Brain Cognitive Development (ABCD) Study^℠. Adjusting for confounders, we identified a latent variable representing 66% of the variance between o

SUBMITTER: Sukumaran K 

PROVIDER: S-EPMC10006642 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature