Imidazolium Salts for Candida spp. Antibiofilm High-Density Polyethylene-Based Biomaterials.

ABSTRACT: The species of Candida present good capability to form fungal biofilms on polymeric surfaces and are related to several human diseases since many of the employed medical devices are designed using polymers, especially high-density polyethylene (HDPE). Herein, HDPE films containing 0; 0.125; 0.250 or 0.500 wt% of 1-hexadecyl-3-methylimidazolium chloride (C₁₆MImCl) or its analog 1-hexadecyl-3-methylimidazolium methanesulfonate (C₁₆MImMeS) were obtained by melt blending and posteriorly mechanically pressurized into films. This approach resulted in more flexible and less brittle films, which impeded the Candida albicans, C. parapsilosis, and C. tropicalis biofilm formation on their surfaces. The employed imidazolium salt (IS) concentrations did not pr

SUBMITTER: Martins Leal Schrekker C 

PROVIDER: S-EPMC10007465 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature