New proposal of viral genome representation applied in the classification of SARS-CoV-2 with deep learning.

ABSTRACT:

Background

In December 2019, the first case of COVID-19 was described in Wuhan, China, and by July 2022, there were already 540 million confirmed cases. Due to the rapid spread of the virus, the scientific community has made efforts to develop techniques for the viral classification of SARS-CoV-2.

Results

In this context, we developed a new proposal for gene sequence representation with Genomic Signal Processing techniques for the work presented in this paper. First, we applied the mapping approach to samples of six viral species of the Coronaviridae family, which belongs SARS-CoV-2 Virus. We then used the sequence downsized obtained by the method proposed in a deep learning architecture for viral classification, achieving an accuracy of 98.35%, 99.08%, and 99.69% for the 64

SUBMITTER: de Souza LC 

PROVIDER: S-EPMC10007673 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature