Charge Regulation of Poly(acrylic acid) in Solutions of Non-Charged Polymer and Colloids.

ABSTRACT: Weak polyelectrolytes (WPEs) are responsive materials used as active charge regulators in a variety of applications, including controlled release and drug delivery in crowded bio-related and synthetic environments. In these environments, high concentrations of solvated molecules, nanostructures, and molecular assemblies are ubiquitous. Here, we investigated the effect of high concentrations of non-adsorbing, short chains of poly(vinyl alcohol), PVA, and colloids dispersed by the very same polymers on charge regulation (CR) of poly(acrylic acid), PAA. PVA does not interact with PAA (throughout the full pH range) and thus can be used to examine the role of non-specific (entropic) interactions in polymer-rich environments. Titration experiments of PAA (mainly 100 kDa in dilute solutions, no a

SUBMITTER: Yekymov E 

PROVIDER: S-EPMC10007678 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature