Associations between dietary intake and glucose tolerance in clinical and metabolomics-based metabotypes.

ABSTRACT:

Background

Metabotyping is a novel concept to group metabolically similar individuals. Different metabotypes may respond differently to dietary interventions; hence, metabotyping may become an important future tool in precision nutrition strategies. However, it is not known if metabotyping based on comprehensive omic data provides more useful identification of metabotypes compared to metabotyping based on only a few clinically relevant metabolites.

Aim

This study aimed to investigate if associations between habitual dietary intake and glucose tolerance depend on metabotypes identified from standard clinical variables or comprehensive nuclear magnetic resonance (NMR) metabolomics.

Methods

We used cross-sectional data from participants recruited through advertisements a

SUBMITTER: Rundblad A 

PROVIDER: S-EPMC10007735 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature