Using pressure-driven flow systems to evaluate laser speckle contrast imaging.

ABSTRACT:

Significance

Microfluidic flow phantom studies are commonly used for characterizing the performance of laser speckle contrast imaging (LSCI) instruments. The selection of the flow control system is critical for the reliable generation of flow during testing. The majority of recent LSCI studies using microfluidics used syringe pumps for flow control.

Aim

We quantified the uncertainty in flow generation for a syringe pump and a pressure-regulated flow system. We then assessed the performance of both LSCI and multi-exposure speckle imaging (MESI) using the pressure-regulated flow system across a range of flow speeds.

Approach

The syringe pump and pressure-regulated flow systems were evaluated during stepped flow profile experiments in a microfluidic device using an inlin

SUBMITTER: Sullender CT 

PROVIDER: S-EPMC10007838 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature