Clinical significance and changes to the immune microenvironment of colorectal cancer patients with liver metastasis.

ABSTRACT:

Background

Liver metastasis is common in colorectal cancer patients. Immunotherapy covers a wide range of tumor types and is safer than traditional radiotherapy and chemotherapy. However, its overall effective rate is only 20-40%. At present, there is a lack of relevant research clarifying whether the changes and clinical significance of the immune microenvironment in colorectal cancer patients with liver metastasis are conducive to enhancing the promotion and further improving the efficacy of immunotherapy.

Methods

We retrospectively collected the data of 50 colorectal cancer patients with liver metastasis treated in Chongqing University Cancer Hospital from January 2017 to January 2019. Liver metastatic cancer tissues and normal liver tissues were collected to detect the l

SUBMITTER: Wang T 

PROVIDER: S-EPMC10007917 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature