Antimicrobial resistance in topical treatments for microbial keratitis: protocol for a systematic review and meta-analysis.

ABSTRACT:

Introduction

There is evidence for increased resistance against the antimicrobials used to treat keratitis. This review aims to provide global and regional prevalence estimates of antimicrobial resistance in corneal isolates and the range of minimum inhibitory concentrations (MIC) with their associated resistance breakpoints.

Methods and analysis

We report this protocol following Preferred Reporting Items for Systematic Review and Meta-Analyses Protocols guidelines. We will conduct an electronic bibliographic search in MEDLINE, EMBASE, Web of Science and the Cochrane Library. Eligible studies will report in any language data for the resistance or MIC for antimicrobials against bacterial, fungal or amoebic organisms isolated from suspected microbial keratitis. Studies that on

SUBMITTER: Tuft S 

PROVIDER: S-EPMC10008341 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature