Systematic investigation of the mechanism of herbal medicines for the treatment of prostate cancer.

ABSTRACT: Due to various unpleasant side effects and general ineffectiveness of current treatments for prostate cancer (PCa), more and more people with PCa try to look for complementary and alternative medicine such as herbal medicine. However, since herbal medicine has multi-components, multi-targets and multi-pathways features, its underlying molecular mechanism of action is not yet known and still needs to be systematically explored. Presently, a comprehensive approach consisting of bibliometric analysis, pharmacokinetic assessment, target prediction and network construction is firstly performed to obtain PCa-related herbal medicines and their corresponding candidate compounds and potential targets. Subsequently, a total of 20 overlapping genes between DEGs in PCa patients and the target genes of

SUBMITTER: Wang J 

PROVIDER: S-EPMC10008508 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature