Statistical Fragility of Venous Thromboembolism Prophylaxis Following Total Joint Arthroplasty.

ABSTRACT:

Background

Statistical fragility is a quantitative measure of the robustness of the statistical conclusions drawn in a study. Although statistical fragility has been comprehensively evaluated in the arthroplasty literature, the statistical fragility of large-scale randomized trials evaluating venous thromboembolism (VTE) prophylaxis has not been evaluated. The purpose of this study was to determine the utility of applying the fragility index (FI) and the fragility quotient (FQ) analysis to randomized controlled trials (RCTs) evaluating VTE prophylaxis following total joint arthroplasty.

Methods

A systematic review was performed by searching multiple databases to identify RCTs that evaluated VTE prophylaxis following total joint arthroplasty from 2000 to 2020. The FI was dete

SUBMITTER: Sequeira SB 

PROVIDER: S-EPMC10008837 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature