Isolation, identification, and pathogenicity analysis of newly emerging gosling astrovirus in South China.

ABSTRACT: Goose astroviruses (GoAstV) cause fatal gout and decrease product performance in the waterfowl industry across the world. Since no effective vaccines are available, studies on the epidemiology of the virus are necessary for vaccine development. In this study, we collected 94 gout samples from goose farms in the Guangdong Province of South China. Among them, 87 samples (92.6%) tested positive for GoAstV, out of which five GoAstV strains were isolated after four generations of blind transmission through healthy 13-day-old goose embryos. The whole genome of the isolates was sequenced and further analyzed by comparing the sequences with published sequences from China and other parts of the world. The results of the alignment analysis showed that nucleotide sequence similarities among the five

SUBMITTER: Xu J 

PROVIDER: S-EPMC10008898 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature