Pan-cancer analysis reveals potential of FAM110A as a prognostic and immunological biomarker in human cancer.

ABSTRACT:

Background

Despite great success, immunotherapy still faces many challenges in practical applications. It was previously found that family with sequence similarity 110 member A (FAM110A) participate in the regulation of the cell cycle and plays an oncogenic role in pancreatic cancer. However, the prognostic value of FAM110A in pan-cancer and its involvement in immune response remain unclear.

Methods

The Human Protein Atlas (HPA) database was used to detect the expression of FAM110A in human normal tissues, the Tumor Immune Estimation Resource (TIMER) and TIMER 2.0 databases were used to explore the association of FAM110A expression with immune checkpoint genes and immune infiltration, and the Gene Set Cancer Analysis (GSCA) database was used to explore the correlation betwee

SUBMITTER: Zhong H 

PROVIDER: S-EPMC10008925 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature