Thyroid autoimmunity and adverse pregnancy outcomes: A multiple center retrospective study.

ABSTRACT:

Background

The relationship between thyroid autoimmunity (TAI) and adverse pregnancy outcomes is disputable, and their dose-dependent association have not been fully clarified.

Objective

To investigate the association and dose-dependent effect of TAI with multiple maternal and fetal-neonatal complications.

Methods

This study is a multi-center retrospective cohort study based on singleton pregnancies of three medical college hospitals from July 2013 to October 2021. The evolution of thyroid function parameters in TAI and not TAI women were described, throughout pregnancy. The prevalences of maternal and fetal-neonatal complications were compared between the TAI and control group. Logistic regression was performed to study the risk effects and dose-dependent effects of

SUBMITTER: Xu Y 

PROVIDER: S-EPMC10008944 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature