The bidirectional association of 24-h activity rhythms and sleep with depressive symptoms in middle-aged and elderly persons.

ABSTRACT:

Background

In older populations disturbed 24-h activity rhythms, poor sleep, and depressive symptoms are often lingering and co-morbid, making treatment difficult. To improve insights into these commonly co-occurring problems, we assessed the bidirectional association of sleep and 24-h activity rhythms with depressive symptoms in middle-aged and elderly persons.

Methods

In 1734 participants (mean age: 62.3 ± 9.3 years, 55% women) from the prospective Rotterdam Study, 24-h activity rhythms and sleep were estimated with actigraphy (mean duration: 146 ± 19.6 h), sleep quality with the Pittsburgh Sleep Quality Index, and depressive symptoms with the Center for Epidemiological Studies Depression scale. Repeated measures were available for 947 participants (54%) over a median foll

SUBMITTER: de Feijter M 

PROVIDER: S-EPMC10009400 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature