A population-wide analysis of the familial risk of suicide in Utah, USA.

ABSTRACT:

Background

The degree to which suicide risk aggregates in US families is unknown. The authors aimed to determine the familial risk of suicide in Utah, and tested whether familial risk varies based on the characteristics of the suicides and their relatives.

Methods

A population-based sample of 12 160 suicides from 1904 to 2014 were identified from the Utah Population Database and matched 1:5 to controls based on sex and age using at-risk sampling. All first through third- and fifth-degree relatives of suicide probands and controls were identified (N = 13 480 122). The familial risk of suicide was estimated based on hazard ratios (HR) from an unsupervised Cox regression model in a unified framework. Moderation by sex of the proband or relative and age of the proband at

SUBMITTER: Bakian AV 

PROVIDER: S-EPMC10009406 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature