Multiple tendon transfer for a case of radial nerve palsy in hereditary neuropathy with liability to pressure palsy

ABSTRACT: ABSTRACT Hereditary neuropathy with liability to pressure palsy (HNPP) is a rare autosomal dominant disease characterized by focal, recurrent, demyelinating peripheral neuropathies. It is caused by deletions of the gene encoding for peripheral myelin protein 22 (PMP22) on chromosome 17. While it may range widely, the most common clinical presentation is an acute, focal mononeuropathy with numbness or muscle weakness after trauma or compression. Diagnostic tools include electrophysiological studies, genetic tests and nerve biopsies. There is no standard surgical or pharmacological treatment. The course of the disease is usually benign, with spontaneous improvement after most episodes of peripheral nerve palsy. HNPP is best managed by early detection, preventative measures, and subsequent tr

SUBMITTER: Palumbo F 

PROVIDER: S-EPMC10009638 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature