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Galectins can serve as biomarkers in COVID-19: A comprehensive systematic review and meta-analysis.


ABSTRACT:

Background

Galectins are an eleven-member class of lectins in humans that function as immune response mediators and aberrancies in their expression are commonly associated with immunological diseases. Several studies have focused on galectins as they may represent an important biomarker and a therapeutic target in the fight against COVID-19. This systematic review and meta-analysis examined the usefulness of clinical assessment of circulating galectin levels in patients with COVID-19.

Methods

International databases including PubMed, Scopus, Web of Science, and Embase were systematically used as data sources for our analyses. The random-effect model was implemented to calculate the standardized mean difference (SMD) and a 95% confidence interval (CI).

Results

A total

SUBMITTER: Behnoush AH 

PROVIDER: S-EPMC10009778 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature