Modulation of vulvovaginal atrophy (VVA) by Gelam honey in bilateral oophorectomized rats.

ABSTRACT:

Introduction

Vulvovaginal atrophy (VVA) is a common condition in post-menopausal women. Symptoms of VVA include dyspareunia, vaginal dryness, vaginal and/or vulvar itching, burning and soreness, dysuria and vaginal bleeding accompanying sexual activity. These symptoms are physiological responses to hypoestrogenicity, inducing atrophy of the vagina epithelia and sudden reduction in mucous production. Prevailing therapy for VVA is hormone replacement therapy (HRT), notably estrogen, progesterone or a combination of the two. However, using HRT is associated with an increased incidence of breast and endometrial cancer, venous thromboembolism in the lungs and legs, stroke and cardiovascular complications.

Methods

This study evaluated Malaysian Gelam honey as a nutraceutical alter

SUBMITTER: Ismail NH 

PROVIDER: S-EPMC10010262 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature