Predictors of urinary biomarker concentrations of phthalates and some of their replacements in children in the Project Viva cohort.

ABSTRACT:

Background

Some phthalates are still widely used in food packaging, toys, and personal care products, and links to adverse health have motivated substitution with replacement chemicals. Few studies have examined patterns and predictors of phthalate replacement biomarkers in children.

Objective

To examine associations of sociodemographic, dietary, and urine collection characteristics with urinary concentrations of biomarkers of select phthalates and their replacements in mid-childhood.

Methods

We studied 830 children ages 6-10 years in 2007-2010 in a Boston-area cohort. We quantified urinary metabolites and summed their concentrations to calculate biomarkers of the concentrations of ten parent phthalates/replacements. We used linear regression to examine mutually adjus

SUBMITTER: Kalloo G 

PROVIDER: S-EPMC10010945 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature