Point-of-care neutrophil CD64 as a rule in diagnostic test for bacterial infections in the emergency department.

ABSTRACT:

Introduction

Bacterial infections are frequently seen in the emergency department (ED), but can be difficult to distinguish from viral infections and some non-infectious diseases. Common biomarkers such as c-reactive protein (CRP) and white blood cell (WBC) counts fail to aid in the differential diagnosis. Neutrophil CD64 (nCD64), an IgG receptor, is suggested to be more specific for bacterial infections. This study investigated if nCD64 can distinguish bacterial infections from other infectious and non-infectious diseases in the ED.

Methods

All COVID-19 suspected patients who visited the ED and for which a definitive diagnosis was made, were included. Blood was analyzed using an automated flow cytometer within 2 h after presentation. Patients were divided into a bacterial,

SUBMITTER: van de Ven NLM 

PROVIDER: S-EPMC10010956 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature