Quantification of sulcal emergence timing and its variability in early fetal life: Hemispheric asymmetry and sex difference.

ABSTRACT: Human fetal brains show regionally different temporal patterns of sulcal emergence following a regular timeline, which may be associated with spatiotemporal patterns of gene expression among cortical regions. This study aims to quantify the timing of sulcal emergence and its temporal variability across typically developing fetuses by fitting a logistic curve to presence or absence of sulcus. We found that the sulcal emergence started from the central to the temporo-parieto-occipital lobes and frontal lobe, and the temporal variability of emergence in most of the sulci was similar between 1 and 2 weeks. Small variability (< 1 week) was found in the left central and postcentral sulci and larger variability (>2 weeks) was shown in the bilateral occipitotemporal and left superior temporal sulc

SUBMITTER: Yun HJ 

PROVIDER: S-EPMC10011016 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature